Tag: cloning

Cloning

“No civilization can survive if it treats human life as a merely instrumental good and the deaths of innocents as a legitimate objective. Yet, America is dangerously close to forgetting that human life – all human life – is a gift to be treasured. The life of a human being is an intrinsic good, not something whose value is conditional upon its usefulness to others or to the state. The life of every human being is worthy – equally worthy – of care and respect. Human beings need not prove their moral worth by demonstrating sentience, or self-awareness, or a certain level of cognitive ability.”
~From Building A Culture of Life


Until February 1997, the human cloning of Aldous Huxley’s Brave New World was a futuristic, science fiction scenario. On February 27, 1997, the chills of reality went down our spines with the announcement that English scientists had cloned a sheep named Dolly. Promptly following this news, researchers in Oregon on March 1, 1997, announced that a Rhesus monkey had been cloned. The reality of animal cloning stares us in the face and human cloning is around the corner. Science has an unquenchable thirst to do what is possible, sometimes without regard to moral implications.

Proponents of human cloning rush forward with proposals for its use that on the surface appear benevolent. Advocates mention replacing a dead child with a genetic twin or creating a reservoir of genetically-matched material for spare parts for diseased organs such as bone marrow, livers, kidneys, etc. The National Bioethics Advisory Commission (NBAC) has recommended that clones grown outside the womb could provide genetic advances for fighting diseases such as cystic fibrosis, Parkinson’s disease and cancer. Individuals and groups are stepping out to be identified as “pro-clone.” The right to choose philosophy, with which prolife groups are so familiar, will be the ultimate justification for these individuals.

Cloning, also called “somatic cell nuclear transfer (donor cell),” involves a transfer of a nucleus of a somatic cell (any ‘body’ cell other than an egg or sperm) to an egg that has had its nucleus removed. This egg is stimulated by a tiny electrical current to begin to develop. The embryo later is transferred from the lab to the host uterus to complete the development of the new individual. This new individual is not an exact duplicate of the donor since a small genetic contribution is made by the mitochondrial DNA of the host cell.

In response to the introduction of Dolly, President Clinton charged the NBAC with making recommendations on human cloning. On June 9, 1997, based on the NBAC report, the President released his “Cloning Prohibition Act of 1997,” stating, “Banning human cloning reflects our humanity. It is the right thing to do. Creating a child through this new method calls into question our most fundamental beliefs.” This act, however, is only a temporary, five-year ban prohibiting cloned humans from being created and born. It does allow federally funded unrestricted research on cloned embryonic human beings. The ‘moratorium’ announced by the President on federally funded research applies only to research intended to “create [bring to birth] a human being.”

Right to Life of Michigan finds human cloning to be an inherent violation of human dignity. As with abortion and assisted reproductive technologies, such as in vitro fertilization, human cloning research denies the most fundamental of human rights — the right to life. The research process inevitably requires scientists to destroy and discard their ‘failed’ experiments. For example, it took 277 attempts at cell manipulation and 29 embryo implants before the sheep, Dolly, was produced.

Cloning would further violate human dignity by denying the intrinsic value of each human life, thereby viewing human beings as products or commodities. For this same reason we already oppose surrogate parenting contracts, genetic screening of embryos before uterine implanting and sex selection abortion. Cloning could not possibly respect the intrinsic value of the person created, because a cloned person will not be created simply for their value as a person. There will always be an intended and specific utility attached to a cloned person because he or she was created with a particular genetic make-up for some purpose. Any action taken to create or destroy human beings based on their genetic qualities denies their intrinsic value.

Right to Life of Michigan strongly advocates for the passage of tightly written legislation at the national and state level that will permanently ban all human cloning including research on embryos. If human cloning proceeds, our minds can conjure up many scenarios of abuse of human cloning as our narcissistic society creates human beings not in God’s own image but in our own.

(October 8, 1997)

Genetic Engineering

As participants in the rapidly changing scene of this fabulous century, we are ever aware of the giant strides that science has taken into the unknown. The awesome job of splitting the atom has been done, spinning off in its wake both the evil mushroom clouds over Hiroshima and Nagasaki, and the bright hope that nuclear energy may yet be harnessed to the world’s needs. In the DNA discoveries, the very core of Life was penetrated proving with finality that a life is indeed begun when a father’s sperm fertilized the mother’s ovum to form a unique individual, whom, if lost, will never be replaced. And in the space experiments, we have all been spectators of the stirring adventure when men walked on the moon.

Scientific activity is, of itself, inherently good since it is an honest search for the truth about every physical thing under the sun. The men and women engaged in it invest their lives in this act of discovery with the hope that their work will benefit the society in which they live. (“Let knowledge grow, that life may be enriched” was the academic motto of the University of Chicago where nuclear fission first took place.)

The fruits of these labors – the hard won facts of science – are morally neutral in themselves, but the applied uses of their knowledge may not be. We must face the fact that scientific research “has gradually assumed increasingly precise direction . . . ” Whereas in the past it was a discipline of discovery, “it is characterized now more by intent than by discovery.”1 We must be prepared for the fact that as the applied sciences continue their inexorable thrust into the unknown, they will occasion moral dilemmas exacting the last drop of wisdom of which society is capable. In fact, this situation has already begun.

It is to be fervently wished that Science would police itself, and failing that, the high offices of government would step in, but we have seen confusion compounded in HEW guidelines, and action by committee is sluggish and indistinct at best. If Right to Life of Michigan deserves to consider itself a defender of human life, it must not shrink from the summons to maturity posed by these dilemmas. It must plan to insert its voice at the councils of decision. Perhaps the center state for these dilemmas is occupied by what is known as Genetic Engineering of which the following are part:

Amniocentesis – In approximately the 16th week of pregnancy, a needle may be inserted into the uterus and fluid extracted from the sac surrounding a developing baby. This fluid reveals information about the baby’s physical condition. The procedure was developed as a life saving technique for RH babies and others, but recently it has been turned into an instrument of death. For it is now being used as a screening process for “defective” babies in utero (or even those of an unwanted sex) who are then aborted. We consider this application to be a tragic misuse of amniocentesis and one that is a significant factor in the pressures for planned eugenic perfection of mankind. (It is also the focal point of our controversy with March of Dimes.)

In Vitro Fertilization (Test Tube Babies) – Despite our continuing sympathy for couples unable to procreate their own children and our personal understanding of the natural yearning to do so that is part of the human personality, we must take a negative view of the efforts of in vitro fertilization as we see them today and as evidenced by the work of the British doctors Steptoe and Edwards. This is because we may not ignore the ethical questions of (a) destroying the fertilized ova which do not measure up for implantation, and (b) abortion of the developing fetus which is discovered through amniocentesis to be “defective.”

Further facets of genetic engineering in the blueprint stage are nuclear transplantation or cloning, monitored mating, and the human-plant and human-animal hybrids. On the subject of monitored mating, we note that no less an authority than Nobel Laureate Linus Pauling has said . . . “I have suggested that there should be tattooed on the forehead of every young person a symbol showing possession of the sickle-cell gene or whatever other similar gene . . . that he has been found to possess in a single dose. If this were done, two young people carrying the same seriously defective gene in a single dose would recognize this situation at first sight and would refrain from falling in love with one another. It is my opinion that legislation along this line, compulsory testing for defective genes before marriage, and some form of public or semi-public display of this possession, should be adopted.”2 (Emphasis ours.)

However “far out” these ideas may sound, they are spoken unsmilingly in high circles. These portents are disturbing, and the subject matter is extremely complex. Yet we must not assume an attitude of helplessness among the ethical confusion of our times. “We are merely required to do what all men and women have always done; to rediscover and apply the truth to our own circumstances . . . “3 The alleged technological imperative of “what we can do we must do” is suggestive of knowledge without an ethic or conscience. Let us instead adopt the more humane imperative of Professor Paul Ramsey of Princeton University who says, “The good things that men do can be made complete only by the things they refuse to do.”4


1 Bryan Griffin, The Human Life Review, Summer, 1977, p. 32, The Human Life Foundation, Inc.; New York, NY.

2 Linus Pauling, “Foreword to reflections on the New Biology,” UCLA Law Review 15:2; Feb. 1968, p. 269 as quoted by Charles Frankel, “The Specter of Eugenics,” Commentary, March 1974, p. 28.

3 Bryan Griffin, op. cit. p. 35.

4 William Smith, “Procreation Is Not For the Laboratory,” Human Life Review, Fall, 1978, p. 35. The Human Life Foundation, Inc.; New York, NY.

Human Embryonic Stem Cell Research

Is It Necessary?

Embryonic stem cell research is one of the most controversial issues of the day.  For many people, the reality that stem cells can be obtained from adults, fat and umbilical cord blood, is unknown.

The following information gives examples of arguments for the side advocating the killing of embryos for research and then gives rebuttals to these arguments. For many people, the reality that stem cells can be obtained from adults, fat and umbilical cord blood is unknown. Educating others that stem cell research can be pursued without taking the life of a human embryo is needed. Prolife people also want to see cures for diseases, but not at the expense of members of the human race.


If they say….
Stem cells aren’t alive. If stem cells possess life-saving possibilities, why shouldn’t they be used for research?

You say….
You are right, stem cells aren’t alive. However, a living human embryo must be destroyed in order to obtain embryonic stem cells. Every time embryonic stem cells are extracted from a human embryo, a unique individual is destroyed. The removed stem cells would have developed into the child’s heart, kidneys and all of the 210 different kinds of tissue found in the human body1.

Embryos have the 46 chromosomes that make them human. It is already decided if they will be a boy or a girl. It is already decided what color eyes they will have. From the first day of conception until death, nothing has or will be added to them except food and oxygen.


If they say….
It’s just a frozen fertilized egg. What’s the big deal?

You say….
This statement is false. A fertilized egg is the term used to describe a one-cell human in its first day of development. A fertilized egg does not have any stem cells to extract because it is only one cell. Embryonic stem cells are removed from embryos who are around a week old. These embryos are called blastocysts and they number several hundred cells.

Life begins at conception. We all began life when a sperm joined an ovum. The size of a human body doesn’t give life value. Is a 6’5, 300-pound man more valuable than a newborn child?

It is also important to mention that an embryo is no less valuable if she is frozen than if she is in her mother’s womb. The stage of development, temperature, and size of a child don’t determine its value. The fact that an embryo is a human life is what makes her priceless.


If they say…
It doesn’t even look like a human.

You say….
Actually, it does look human. This is exactly how every human looks during this stage of development. Every human looked the same shortly after conception. Just because people aren’t as familiar with this stage of development doesn’t mean that an embryo isn’t human and doesn’t look like a human.

Many people have different deformities or peculiarities that take away from their ability to look like the “ideal human.” That doesn’t mean that they’re not human and that they don’t have the same rights as other humans. The way something looks doesn’t make it human.

Some believe stem cells from human embryos are human enough for research, but not human enough to join the human family. This logic defies the reality that life begins at conception, a truth some researchers and politicians would like to ignore.


If they say….
All of these embryos will just be destroyed anyway, so why not use them for helpful research?

You say….
Embryonic research advocates act like all of the embryos in fertility clinics that aren’t used will be thrown away. This, however, is simply not the case. The parents generally have at least two other options. First, preserve the embryos for possible future use (chosen by about 90%). Two, donate the embryos to another couple so they can have a child.

Even if the embryos are going to be destroyed that doesn’t mean that we have the right to experiment with their bodies. Was it right for Nazi doctors to experiment with concentration camp prisoners that were going to be killed? Is it right for us to experiment with convicts on death row? The obvious answer is no. As a civilized society, we recognize the importance of human life. In order to stay a civilized society we can’t abandon our respect for every individual human being.

It is theorized that embryos from fertilization clinics will be used for the initial experiments. However, if these experiments are successful, some in the biotechnology community have anticipated that the supply of embryos from clinics wouldn’t be enough. This is where human cloning enters the picture. During a Congressional Committee, Biotechnology Industry Organization said that the cloning of embryos “are a critical and necessary step in the production of sufficient quantities of vigorous replacement cells for the clinical treatment of patients.”


If they say….
Embryos are the only place to find stem cells.

You say….
There are many life-affirming alternatives to stem cells taken from destroyed embryos. Initially, alternative stem cell research was not extensive because alternative stem cells were thought to be less available and versatile. However, there have been many recent breakthroughs in the use of stem cells that are derived from alternatives to embryos. The most promising of these alternative methods is the use of adult stem cells. All people have stem cells located in blood, bone marrow, and brains. In rats and mice, it has been found that scientists can use key cells from adult bone marrow and can rebuild a damaged heart—actually creating new heart muscle and blood vessels2. The British Medical Journal has stated that research on embryonic stem cells “may soon be eclipsed by the more readily available and less controversial adult stem cells3.” Adult bone marrow stem cells have been shown to form tissues including bone, muscle, fat, liver, and neural cells4. There is also the case of an 18 year-old women whose spinal cord was severed in automobile accident. Thanks to white blood cells from her own skin and bone marrow that have been injected into the damaged area, she now has regained bladder control and recovered significant motor function in her legs.

Researchers have also found stem cells in human fat. Researchers at the University of Pittsburgh and UCLA got fat from liposuction patients and then collected stem cells from this fat which grew into muscle, bone, and cartilage cells5.

Another important note is that stem cells derived from the bodies of patients don’t face the possibility of rejection, unlike embryonic stem cells. This rejection can lead to death since the cells can’t be extracted once the are injected.

Yet another promising alternative to embryonic stem cell research that doesn’t have ethical implications is research on stem cells found in the blood of umbilical cords. The small amount of blood found in umbilical cords after birth is rich in stem cells. Researchers have said “Umbilical cords discarded after birth may offer a vast new source of repair material for fixing brains damaged by strokes and other ills, free of the ethical concerns surrounding the use of fetal tissue6.”

These preceding examples are only a few of the many alternatives to human embryo stem cells. For a long list of alternative research and findings to go to and look at the current clinical and potential applications of adult stem cells.


If they say….
Without embryonic stem cell research, the great potential of stem cells is wasted.

You say….
As mentioned above there are many life-affirming alternatives to embryonic stem cell research. Continued research is needed for these kinds of research but if the federal government begins to fund embryonic stem research that means that there will be less federal funds for research on adult stem cells. On March 8, 2001, a group of plaintiffs, including the Christian Medical Association filed suit against the NIH to prevent federal funding of embryonic stem cell research. The lawsuit argued that federal funding of embryonic stem cell research would cut the funding available for adult stem cell research7.


If they say….
Scientists should be allowed to do the research. Who is the government to stop them?

You say….
The Bush administration isn’t deciding if embryonic stem cell research should be illegal. It is deciding if federal funds should go towards supporting this kind of research. There is a law, called the “Dickey Amendment,” which states that federal funds can’t be used for “research in which a human embryo or embryos are destroyed, discarded, or knowingly subjected to risk of injury or death.” The Clinton administration got around this law by accepting the NIH (National Institutes of Health) Guidelines that separated the research on the embryonic stem cells from the act of obtaining those stem cells. So researchers would have to privately fund the obtaining of stem cells through the destruction of human embryos but could get public funds for research on those cells. Our government shouldn’t be involved in promoting research that involves and requires the destruction of innocent human lives.


If they say….
Embryonic stem cells have already helped people. Isn’t that evidence enough?

You say….
Actually, embryonic stem cells have probably done more damage than help to humans. The whole argument behind research on embryonic stem cells is based on potential cures not current cures. There are a few problems with using embryonic stem cells in actual surgeries.

One problem is that these cells are completely undifferentiated so they don’t always become what researchers want them to become. There was an experiment in China, where a man with Parkinson’s was injected with fetal and embryo cells. He died unexpectedly after improving briefly. His autopsy revealed that his death was caused by the “unexpected growth of bone, skin, and hair in his brain, material the authors theorized resulted from the transformation of undifferentiated stem cells into non-neural, and therefore deadly, tissues8.”

Another problem is that the undifferentiated stem cells could become cancer cells. In an interview with Technology Review, a Massachusetts Institute of Technology publication, University of Pennsylvania bioethicist Glenn McGee said, “The emerging truth in the lab is that pluripotent (embryonic) stem cells are hard to rein in. The potential that they would explode into a cancerous mass after a stem cell transplant might turn out to be the Pandora’s box of stem cell research.”


If they say….
This kind of research could save lives and we should explore all areas of research that could find ways to cure such a wide array of diseases.

You say….
Even though this research could be helpful, it is still never ethically correct to sacrifice the life of one human to save another without their consent. This kind of utilitarian thinking was the same kind of rationale used by Nazi scientists and during syphilis experiments on African Americans in Tuskegee, Alabama.

Medical advancement should continue but not through the taking of human life. No human being should be forced to be made the subject of research without their permission, especially if that research leads directly to their destruction.


References:
1 Prentice, D., No Fountain of Youth, Regeneration Online.
2 Bazell, R. “Approach may repair heart damage,” NBC Nightly News, 3/30/01.
3 Jofeson, D., Adult Stem Cells May be Redefinable, British Medical Journal, January 30, 1999; 318, p. 282.
4 Prentice, D., No Fountain of Youth, Regeneration Online.
5 Lemonick, M., Who Will Live Longest?, Time, April 23, 2001, p. 64
6 “Umbilical cords could repair brains,” Associated Press, 2/20/01.
7 Boston Globe, 3/14/2001.
8 Smith, W. “The Politics of Stem Cells: The good news you never hear.”, The Weekly Standard, March 26, 2001/Vol 6, Number 27

Special thanks to Right to Life of Michigan for providing this article.